first choice is always the pump shotgun..
My load out is #8 bird first, then #00 buckshot.
theory behind it is birdshot will only penetrate so many layers of drywall, so downrange risk of family in a 'gotta shoot' moment is minimized, pepper someone's torso with birdshot while you maneuver to a 'safer' downrange backdrop, or wait for another family member to provide backup.
I've been peppered with #8 at around 100 yds and with several layers on in a bird field. It'll make you say words you don't want grandma to know you know, even at distance.
It shreds yotes and possums up to about 20 YD, so I know what damage to expect.
Still don't want to use one in my house, but ain't gonna risk my wife, kids or grandkids' lives on a whacked out crackhead..