Killed 2 gooduns last year with a 243 Tikka and 95gr Federal Fusion factory ammo. First time ever with a 243 but used many different cartridges in the past. One was a really good 140" 10 at aprox 250 yards. Gun shoots the factory ammo so well that I couldn't do any better with hand loads. The Federal Fusion 95gr 243 ammo has been the most accurate factory ammo that I have ever seen, and in multiple 243's.
And "energy" or "hitting power" does nothing except allow the bullet to do its job. An animal is no more or no less dead if a bullet stops just under the skin of the far side or if it blows through. The damage done along the way to arteries, organs, spine, bone and brain is what kills. Not the equivalent "hit" of what you feel on your shoulder. Except for small varmints and hollywood, bullets do not drive animals or people sideways, backwards or fling them off their feet.
Put a bullet that is designed for the job you want it to do where it needs to be and it is a short tracking job, if any.