The main thing I dislike about all AI cartridges is the necessity to fire form cases due to the extra time and cost of doing that. I'd rather just go to a 7mm Rem Mag or 7mm STW if I want better performance. Ammo is easier to find and no fire forming for handloads.
You don't have to fireform the 280 AI as Nosler makes brass for it. I just took delivery of a McWhorter 280ai. This is my new favorite cartridge....2950 out of Berger 168's with Reloader 23....Very mild recoil. Extremely accurate....I have a 7 STW but the 280 AI I will be choosing most of the time....
Pic with the dot is a 300 yard group. That is 3 shots that measured less than .4" The other pic is a 500 Yard group that measured 1.15"